Industrial Organic Reactions with Solid Catalysts

Abstract: 

Industrial Organic Reactions with Solid Catalysts.

Antonio Leyva-Pérez

Instituto de Tecnología-Química UPV-CSIC
Group webpage: https://antonioleyvaperez.blogs.upv.es/

Chemical industry moves >€3000 billion worldwide, and it represents the 6% of the gross domestic product in Spain. Thus, the synthesis of chemicals is paramount for industrial development. Industrial organic reactions are little explored with solid material catalysts, since the latter have been traditionally used in fields somewhat away of organic synthesis, such as petrochemistry and water treatment, to name a few. Here, we show different approaches to use (nanostructured) solid catalysts for organic reactions of industrial interest, with potential implementation in real processes. For the sake of illustration, the case of the hydrosilylation of alkenes and alkynes,[1] cyanosilylation of ketones,[2] antitumoral heterocyle formation,[3] carbon-carbon cross-coupling reactions[4] and acetal hydrolysis,[5] will be commented here. Other reactions of potential interest in industrial organic synthesis such as the carbonyl-olefin metathesis,[6] the Büchner [7] and the Nazarov reactions,[8] will be also shown. The talk will describe how the design of a nanostructured solid catalyst is able to completely reverse the regioselectivity of organic reactions, and how supported metal species give access to multifunctional catalysts, where the nanostructured solid-metal interaction plays a key role during the catalysis.